Please use this identifier to cite or link to this item: http://repository.ush.edu.sd:8080/xmlui/handle/123456789/428
Title: HPV Infection in Esophageal Squamous Cell Carcinoma
Other Titles: HPV Infection in Esophageal Squamous Cell Carcinoma
Authors: Yousif Elemam, Ibrahim Bakhit
Keywords: Human papillomavirus, esophageal cancer. Immunohistochemistry
Immunohistochemistry
Human papillomavirus, esophageal cancer
Human papillomavirus
esophageal cancer
cancer
Issue Date: 2-Feb-2016
Publisher: Valley International Journals - International Journal Of Medical Science And Clinical Inventions
Citation: International Journal Of Medical Science And Clinical Inventions
Series/Report no.: Volume 3 issue 2 2016;page no. 1553-1556
Abstract: Carcinomas of esophagus, mostly squamous cell carcinomas, occur throughout the world. There are a number of suspected genetic or environmental etiologies. Oncogenic human papillomavirus (HPV) has been hypothesized as a risk factor for esophageal squamous cell carcinoma. The aims of this review was to estimate the present of HPV by immunohistochemical technique Material and Methods: In this is descriptive retrospective study, which carried out Khartoum state -Sudan, formalin fixed paraffin embedded blocks from 30 patients previously diagnosed as esophageal tumors , Five (4) micron was taken on positively coated slide for immunohistochemical detection of HPV (6, 11, 16, 18, 31, 33, 42, 51, 52, 56 and 58). SPSS version 11.5 computer programs were used to analyze the data, frequencies, and means, the P.value was calculated by Chi square test. Result: The study involved (30) , 13 out of 30 were males (43.3%) and 17(55.7%) were females with (1.3:1) female: males ratio, their age ranging from 25 and 89 years with mean of age about 55.7 years old. HPV was detected in four samples (13.3%) with statistically insignificant difference between HPV infection and type of tumors. Conclusion: . This study demonstrates that the HPV infection rate in ESCC samples is very low, suggesting that HPV is not the etiological cause of ESCC in Sudan.
Description: International Journal Of Medical Science And Clinical Inventions Volume 3 issue 2 2016 page no. 1553-1556 e-ISSN: 2348-991X p-ISSN: 2454-9576 Available Online At: http://valleyinternational.net/index.php/our-jou/ijmsci HPV Infection in Esophageal Squamous Cell Carcinoma 1 Islam Bakri Mohamed elhag , 2Ibrahim Bakhit Yousif Elemam 1BS.c in medical laboratory sciences – AL- Neelain university, Sudan 2Department of Histopathology and Cytology -Faculty of Medical Laboratory Sciences -Shendi UniversitySudan Correspondent contact: Dr. Ibrahim Bakhit Yousif Elemam Faculty of Medical laboratory Sciences, Shendi University- Sudan Email: elemam.ibrahim@yahoo.com
URI: http://hdl.handle.net/123456789/428
ISSN: 2454-9576
Appears in Collections:Researches and Scientific Papers البحوث والأوراق العلمية

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