Please use this identifier to cite or link to this item: http://repository.ush.edu.sd:8080/xmlui/handle/123456789/431
Full metadata record
DC FieldValueLanguage
dc.contributor.authorYousif Elemam, Ibrahim Bakhit-
dc.date.accessioned2018-05-21T09:43:32Z-
dc.date.available2018-05-21T09:43:32Z-
dc.date.issued2018-01-05-
dc.identifier.citationJ. Exp. Zool. India Vol. 21, No. 1, pp. 571-576, 2018en_US
dc.identifier.issn0972-0030-
dc.identifier.urihttp://hdl.handle.net/123456789/431-
dc.description.abstractCervical cancer is one of the commonest female cancers in Sudan due to the absence of HR-HPV screening and vaccination programs.The aim of this study was to screen forthe existence of cervical cancerrelated herpes viruses (HPV, EBV, CMV and EBV) among Sudanese women with cervical cancer. This was analytical case control study conducted in Khartoum state-Sudan during period from October 2013 to June 2016. One hundred and eighty paraffin-embedded tissue blocks were included in this study. Of the 180 tiaaue’s blocks, 98 blocks were from patients with cervical squamous cell carcinoma (case group) and 82 were from cervical tissue’s blocks malignancy-free (control group). Screening for herpes viruses (HPV, EBV, CMV and EBV) were performed using Immunohistochemistry (IHC) techniques. HR-HPV infection was detected in 28.6% of the cases, and 2.4% of the controls.Association between HR-HPVand cervical carcinoma was found to be statistically significant P < 0.0001. CMV infection was detected in 15.3% of the cases and 1.2% of the controls with statistically significant difference, the P < 0.0001. HSV-2 revealed positivity in 6.1% of the cases and in 1.2% of the controls with no statistically significant correlation. EBV was positive in 2% of the cases, while none of the control was found positive. HR-HPV and EBV are prevalent etiological factors that contribute to the etiology of cervical carcinoma in Sudan. HSV-2 and EBVwere insignificantly found in cervical cancerous leions.en_US
dc.description.sponsorshipShendi Universityen_US
dc.language.isoen_USen_US
dc.publisherJournal of Experimental Zoologyen_US
dc.relation.ispartofseriesVol. 21;No. 1, pp. 571-576-
dc.subjectHPV, CMV, HSV, EBV, Cervical SCC, IHC, Sudanen_US
dc.subjectSudanen_US
dc.subjectHPVen_US
dc.subjectCMVen_US
dc.subjectHSVen_US
dc.subjectEBVen_US
dc.subjectCervical SCCen_US
dc.subjectIHCen_US
dc.titleSCREENING FOR HIGH RISK HUMAN PAPILLOMA VIRUS (HR-HPV), CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUS (HS-2) AND EPSTEIN - BARR VIRUS AMONG SUDANESE FEMALES WITH CERVICAL CANCERen_US
dc.title.alternativeSCREENING FOR HIGH RISK HUMAN PAPILLOMA VIRUS (HR-HPV), CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUS (HS-2) AND EPSTEIN - BARR VIRUS AMONG SUDANESE FEMALES WITH CERVICAL CANCERen_US
dc.typeArticleen_US
Appears in Collections:Researches and Scientific Papers البحوث والأوراق العلمية

Files in This Item:
File Description SizeFormat 
SCREENING FOR HIGH RISK HUMAN PAPILLOMA VIRUS (HR-HPV).pdf123.34 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.