Detection of Human Papilloma Virus Type 16 and 18 E6 Early Protein among Sudanese Esophageal Tumors Patients using Immuno histochemistry

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dc.contributor.author Yousif Elemam, Ibrahim Bakhit
dc.date.accessioned 2018-05-21T08:40:38Z
dc.date.available 2018-05-21T08:40:38Z
dc.date.issued 2015-11-30
dc.identifier.citation Detection of Human Papilloma Virus Type 16 and 18 E6 Early Protein among Sudanese Esophageal Tumors Patients using Immuno histochemistry en_US
dc.identifier.issn 2349-0063
dc.identifier.uri http://hdl.handle.net/123456789/427
dc.description.abstract Esophageal cancer is the eight most common cancer worldwide and the sixth cause of cancer related death with squamous cell carcinoma (SCC) accounting for almost half of all esophageal cancers. Oncogenic human papilloma virus (HPV) has been hypothesized as a risk factor for esophageal squamous cell carcinoma. The aims of this review was to estimate the present of (HPV 16 and 18) by immuno histochemical technique In this is descriptive retrospective study, which carried out in Ibn sena HospitalKhartoum-Sudan, formalin fixed paraffin embedded blocks from 30 patients previously diagnosed as esophageal tumors were included (20 of them with esophageal malignant tumor and 10 of them were benign) ,their age ranging from 8-98 years with mean age of 59 years old Five (4) micron was taken on positively coated slide for immuno histochemical detection of HPV (16 and 18). SPSS version 11.5 computer programs were used to analyze the data, frequencies, and means, the P. value was calculated by Chi square test. The study involved (30) subject twenty out of them were males (66.7%) and (33.3%) were females with (2:1) male: female ratio. Sven samples (23.3%) were positive for HPV (16, 18), while 23(76.7%) were negative, with no statistically significant difference between HPV infection and type of tumors. HPV infection, especially type 16, 18 should be considered as a risk factor for esophageal malignancies in Sudan. en_US
dc.description.sponsorship Shendi University en_US
dc.language.iso en_US en_US
dc.publisher World Journal of Biology and Medical Sciences - Published by Society for Advancement of Science en_US
dc.relation.ispartofseries Detection of Human Papilloma Virus Type 16 and 18 E6 Early Protein among Sudanese Esophageal Tumors Patients using Immuno histochemistry;WJBMS 3/01/08/2016
dc.subject Human Papilloma virus, Esophageal Cancer and Immuno histochemistry en_US
dc.subject Human Papilloma virus, en_US
dc.subject Esophageal Cancer and Immuno histochemistry en_US
dc.subject histochemistry en_US
dc.title Detection of Human Papilloma Virus Type 16 and 18 E6 Early Protein among Sudanese Esophageal Tumors Patients using Immuno histochemistry en_US
dc.title.alternative Detection of Human Papilloma Virus Type 16 and 18 E6 Early Protein among Sudanese Esophageal Tumors Patients using Immuno histochemistry en_US
dc.type Article en_US


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